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1.
Rev. méd. Chile ; 149(12)dic. 2021.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1389406

ABSTRACT

Background: Thoracoabdominal aortic aneurysm (TAAA) is an infrequent disease and demands a highly specialized and experienced management. Open repair (OR) is the gold standard but it is associated with significant morbidity and mortality. Paraplegia and renal failure are the most important complications. Aim: To report our results with OR treatment of TAAA. Material and Methods: Descriptive study including all patients with TAAA operated electively and consecutively by OR between 1983 and 2019. Main outcomes are operative mortality, renal and neurological morbidity, and long-term survival. Results: We report 45 operated patients aged 33 to 84 years, 74% males. Aneurysm extension according to Crawford classification was I in 18%, II in 18 %, III in 36% and IV in 29%. Operative mortality was 4%. The frequency of paraplegia or paraparesis at discharge was 9%. No patient was discharged on hemodialysis. Survival at 5 and 10 years were 60% and 40% respectively. Conclusions: OR of TAAA is a complex procedure. Our results show perioperative mortality rates comparable to highly experienced centers. Although being a major procedure, OR remains an alternative to treat this serious condition.

2.
Rev. chil. pediatr ; 89(3): 361-367, jun. 2018. tab
Article in Spanish | LILACS | ID: biblio-959534

ABSTRACT

INTRODUCCIÓN: La tetralogía de Fallot (TF) es la cardiopatía congénita cianótica más frecuente. La insuficiencia pulmonar (IP) y dilatación del ventrículo derecho (VD) son las complicaciones más frecuentes a largo plazo. La resonancia magnética cardiaca (RMC) es el "gold standard" para la evaluación del VD. OBJETIVO: Analizar la información obtenida de las RMC en el seguimiento de pacientes con TF. PACIENTES Y MÉTODO: Se incluyeron RMC realizadas entre 2007 y 2012 a pacientes con TF, reparados con parche transanular (PTA) o ampliación infundibular (AInf) y sin recambio valvular pulmonar (RVP). La fracción de regurgitación pulmonar (FRP), el volumen y función ventricular fueron evaluados. RESULTADOS: Se realizaron 122 RMC a 114 pacientes. Edad promedio al examen 15,4 ± 7,4 años. 53,3% presentó IP severa (> 40%). La media del volumen de fin de diástole del VD (VFDVD) fue 157,3 ± 38,6 ml/m2, fin de sístole (VFSVD) de 85,3 ± 27 ml/m2 y fracción de eyección (FEVD) 46,4 ± 7,1%. 48,4% presentaba un VFDVD mayor de 150 ml/m2 y el 32,8% mayor a 170 ml/ m2. El PTA se relacionó con mayores volúmenes de VD que la AInf. VFDVD mayor a 170 ml/m2 mostraron peor FEVD (FEVD 47,9 ± 7% vs 43,2 ± 6,4%, p < 0,01). DISCUSIÓN: Casi la mitad mostró una significativa dilatación del VD demostrando que la indicación de RMC es tardía en el seguimiento. El PTA se asoció con mayores VFDVD y VFSVD pero no a peor FEVD.


INTRODUCCIÓN: Tetralogy of Fallot (TOF) is the most frequent cyanotic congenital heart disease. Pulmonary regurgitation (PR) and right ventricle (RV) enlargement and dysfunction are the most common long-term complications. Cardiac magnetic resonance (CMR) is the gold standard for RV evaluation. OBJECTIVE: To analyze CMR results in the follow-up of TOF patients. PATIENTS AND METHOD: All CMR performed between 2007 and 2012 in TOF patients with transannular patch (TAP) repair or infundibular widening, and without pulmonary valve replacement (PVR) were included. Pulmonary regurgitant fraction (PRF), ventricular end-diastolic (EDV) and end-systolic volume (ESV), and ejection fraction (EF) were examined. RESULTS: 122 CMR were performed in 114 patients. Average age at CMR was 15.4±7.4 years. 53.3% of them presented severe PR (> 40%). RVEDV was 157.3 ± 38.6 ml/m2, RVESV was 85.3 ± 27 ml/m2 and RVEF was 46.4 ± 7.1%. RVEDV was > 150 ml/ m2 in 48.4% and > 170 ml/m2 in 32.8% of patients. Patients with TAP showed larger RV volumes compared with those with infundibular widening. RVEDV > 170 ml/m2 showed worse RVEF that those with lower RVEDV (47.9 ± 7% vs 43.2 ± 6.4%, p < 0.01). CONCLUSION: Almost half of the pa tients showed significant RV enlargement, demonstrating that the indication of CMR is late in their follow-up. TAP was associated with higher RVEDV and RVESV, but no worse RVEF.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Postoperative Complications/diagnostic imaging , Tetralogy of Fallot/surgery , Magnetic Resonance Imaging , Hypertrophy, Right Ventricular/diagnostic imaging , Ventricular Dysfunction, Right/diagnostic imaging , Tetralogy of Fallot/diagnostic imaging , Retrospective Studies , Follow-Up Studies , Hypertrophy, Right Ventricular/etiology , Ventricular Dysfunction, Right/etiology
3.
Rev. méd. Chile ; 139(12): 1544-1552, dic. 2011. ilus, tab
Article in Spanish | LILACS | ID: lil-627588

ABSTRACT

Background: The preferred treatment for ischemic mitral insufficiency is mitral valve repair with a prosthetic ring, because it does not deteriorate left ventricular function, allowing better immediate and long-term results. Aim: To assess long-term results of mitral annuloplasty with a prosthetic ring for ischemic mitral insufficiency. Patients and Methods: One hundred patients (68 men), with a mean age of 65.7 ± 8.6 years were included. They underwent a mitral annuloplasty with a prosthetic ring to treat ischemic mitral insufficiency, between February 1992 and May 2009. Fortyfour had a history of prior myocardial infarction and 46 had an evolving acute coronary syndrome. The inferior left ventricular wall was involved, exclusively or associated with an adjacent wall, in 72 cases. Coronary artery bypass grafts were performed in 92 patients and 32 required intra-aortic balloon pumping at some time during the peri-operative period. Results: Operative mortality was 10% (10 patients). During follow-up 30 patients died, at an average of 39 months after surgery (range: 3-142 months). Actuarial long-term survival rates at 1, 3 and 5 years were 79%, 72% and 64.5%, respectively. Trans esophageal echocardiogram performed in the operating room showed none or minimal residual mitral insufficiency in 96% of the cases. Echocardiographic follow-up was completed in 80% of the survivors; 79% of them had no or minimal mitral insufficiency. Only one patient was re-operated on due to severe mitral insufficiency and 4 required a permanent pacemaker. Conclusions: Considering the critical illness of these patients, good long-term results were observed after treatment of ischemic mitral regurgitation performing a mitral annuloplasty with a prosthetic ring.


Subject(s)
Aged , Female , Humans , Male , Heart Valve Prosthesis Implantation , Mitral Valve Annuloplasty , Mitral Valve Insufficiency/surgery , Follow-Up Studies , Heart Valve Prosthesis Implantation/adverse effects , Heart Valve Prosthesis Implantation/mortality , Kaplan-Meier Estimate , Mitral Valve Annuloplasty/adverse effects , Mitral Valve Annuloplasty/mortality , Mitral Valve Insufficiency/mortality , Mitral Valve Insufficiency/pathology , Reoperation/statistics & numerical data , Survival Rate , Treatment Outcome
4.
Rev. méd. Chile ; 139(2): 150-157, feb. 2011. ilus, tab
Article in Spanish | LILACS | ID: lil-595280

ABSTRACT

Background: Aortic valve stenosis is the most prevalent valvulopathy in the elderly, but it is frequently undertreated. Aim: To assess early and long term results of valve replacement with bioprostheses in patients 70 years old or older with aortic stenosis. Patients and Methods: A review of the database of the Cardiovascular Surgery Service of our hospital, for the period 1990-2007, identified 156 patients with aortic valve stenosis, aged 76.7 ± 4.5 years (67 percent males), that were subjected to an aortic valve replacement with bioprosthesis. Seventy eight (50 percent) were in functional class III-IV. Six patients had emergency surgery. In 67 patients (43 percent) coronary artery bypass graft were performed. Long term mortality was ascertained obtaining death records from Chilean death registry. Results: Operative mortality was 3.2 percent (5 patients). Four patients (2.6 percent) required a reoperation due to bleeding. The mean follow up was 66 ± 41 months. The survival rate at 1, 3 and 5years was 94 percent, 88 percent and 80 percent, respectively. Forty two patients (27 percent) were 80years old or older. In this sub-group, 1 patient (2.3 percent) died during the peri operative period and the estimated survival rate at 1, 3 and 5years was 97 percent, 92 percent, and 80 percent, respectively. Multivariate risk analysis, for the whole group, identified low ejection fraction and concomitant coronary artery bypass graft surgery as predictors of late mortality. Conclusions: Aortic valve replacement for aortic stenosis with bioprostheses in patients 70 years old or older had low perioperative mortality and morbidity and a good long term survival.


Subject(s)
Aged , Aged, 80 and over , Humans , Male , Aortic Valve Stenosis/mortality , Bioprosthesis , Heart Valve Prosthesis Implantation/mortality , Aortic Valve Stenosis/surgery , Chile/epidemiology , Heart Valve Prosthesis Implantation/methods , Incidence , Survival Analysis , Treatment Outcome
6.
Rev. méd. Chile ; 137(1): 25-30, ene. 2009. ilus, tab
Article in Spanish | LILACS | ID: lil-511840

ABSTRACT

Background: Papillary muscle rupture is a serious complication of myocardial infarction whose only treatment is surgery. Aim: To analyze our most recent surgical experíence with papillary muscle rupture. Patients and Methods: The datábase of our Service was reviewed for the period 1995-2005, to identify patients with papillary muscle rupture. Then, the clinical records and operating protocols were analyzed. Survival and functional class of patients were assessed. Results: Twelve patients (7 men), aged 52 to 89 years, had papillary muscle rupture. They represented 2.2 percent of all mitral procedures for mitral insufficiency and 8.8% of mitral surgeries for ischemic mitral regurgitation, during the study períod. In eight cases myocardial infarction was inferior, in three lateral and in one, anterior. In 10 patients, a mitral replacement was carried-out and in two the mitral valve was repaired. In seven patients, myocardial revascularization was performed. Mean lapse between infarction and surgery was 13.5 days (1 to 85). Two patients died in the perioperative period. Follow-up ranged from 1.7 to 120.4 months. Four patients died during follow-up, 2 due to a cardiovascular cause. Thus, at the end of follow-up 6 patients were alive. All were in functional class III. Conclusions: Papillary muscle rupture is an uncommon complication of myocardial infarction, with considerable operative and ¡ong-term mortality. However, survivors have good quality of life.


Subject(s)
Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Heart Rupture, Post-Infarction/surgery , Papillary Muscles/injuries , Chile/epidemiology , Follow-Up Studies , Heart Rupture, Post-Infarction/mortality , Heart Rupture, Post-Infarction , Papillary Muscles/surgery , Preoperative Care
7.
Rev. méd. Chile ; 136(3): 287-295, mar. 2008. ilus, tab
Article in Spanish | LILACS | ID: lil-484897

ABSTRACT

Background: Cardiac myxoma is the most common primary cardiac tumor. Aim: To evaluate clinical aspects, diagnostic methods and surgical outcomes in patients with cardiac myxoma. Patients and Methods: AH patients who underwent surgical resection of a cardiac myxoma between January 1973 and December 2004 at our institution, were identified and their medical records and diagnostic data reviewed. Results: Thirty seven patients identified (24 women), with a median age of 54 years (range 2-74). The most common symptom was dyspnea (51 percent), followed by embolism (24 percent) and cardiac murmurs (16 percent). The diagnosis was made by echocardiogram in 84 percent of patients. The mean tumor size was 4.9 ± 1.3 cm. The tumor was located in the ¡eft atrium in 83 percent of the patients, right atrium in 8 percent and ¡eft ventricle in 3 percent. Two patients had multiple tumors. Surgical approach was transeptal in 51 percent, left atriotomy in 22 percent, combined transeptal and roof of the left atrium in 19 percent and right atriotomy in 8 percent. The tumor and its attachment base were excised in one piece. There were two operative deaths and five late deaths. The mean follow-up was 11.5 years. The 5, 10, 15 and 20 years survival was 89 percent, 83 percent, 75 percent and 64 percent, respectively. Two patients had recurrence (5.4 percent), at 2 and 25years after surgery, respectively, and the recurrence free survival at 10 and 25years was 97 percent and 73 percent, respectively. Conclusions: Dyspnea was the most common symptom and echocardiogram the main diagnostic method. Surgical treatment was highly effective, with low mortality and recurrence rate, with good long term survival.


Subject(s)
Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Young Adult , Heart Neoplasms/diagnosis , Heart Neoplasms/surgery , Myxoma/diagnosis , Myxoma/surgery , Chile/epidemiology , Postoperative Complications/mortality , Recurrence , Retrospective Studies , Survival Analysis , Young Adult
8.
Rev. méd. Chile ; 135(8): 967-974, ago. 2007. graf, tab
Article in Spanish | LILACS | ID: lil-466495

ABSTRACT

Background: Atrial fibrillation (AF) is a relevant complication after coronary artery bypass grafting (CABG). However there is controversy regarding possible contributing factors. Aim: To study the incidence of AF, its risk factors and its repercussion on hospital stay and charges, in patients undergoing CABG. Material and methods: We prospectively collected information from all patients undergoing CABG in our institution, including demographic, surgical and laboratory variables. Exclusion criteria were chronic AF, recent onset AF and patients who needed additional surgical procedures. The primary endpoint was the incidence of AF during the hospital stay. Secondary endpoints were hospital length of stay and hospital charges. Results: We included 250 patients aged 62±9 years (199 males) in the analysis. Incidence of AF was 22 percent (54 patients). Multivariable analysis showed that age (Odds Ratio (OR) =1.10), previous CABG (OR =9.39), previous use of ACE inhibitors (OR =3.28) and aortic clamp >57 minutes (OR =3.97) were significantly associated with an increased risk of postoperative AF. Previous use of beta-blockers was associated with risk reduction (OR =0.43). Patients who developed AF had a longer hospital stay (p <0.001) and higher hospital charges (p =0.003). Conclusion: AF is a frequent complication in patients undergoing CABG. Risk factors are age, time of aortic clamp, previous CABG and ACE inhibitors. Beta-blockers may prevent its occurrence. Furthermore, AF has a negative impact on both hospital stay and hospital charges.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Atrial Fibrillation/etiology , Coronary Artery Bypass/adverse effects , Coronary Disease/surgery , Coronary Disease/complications , Epidemiologic Methods , Hospitalization , Length of Stay , Postoperative Period
9.
Rev. méd. Chile ; 135(7): 871-878, jul. 2007. ilus, tab
Article in Spanish | LILACS | ID: lil-461914

ABSTRACT

Background: The Cox MAZE III operation for the treatment of atrial fibrillation (AF) is complex and consumes significant operative time. Cryoablation of the pulmonary veins (CPV) is a simpler alternative for patients that require concomitant valvular surgery. Aim: To evaluate CPV in patients with AF submitted to valvular surgery. Patients and Methods: Twenty one patients had simultaneous valvular surgery and CPV, 81 percent of them had permanent AFfor an average of 5 years. Twenty patients had mitral valve disease. The etiology was rheumatic in 14. Average left atrial diameter was 60 mm. In 7patients the mitral valve was replaced, in 5 it was repaired, in 7 both mitral and aortic valve were replaced, in 1 the mitral valve was repaired and the aortic valve was replaced and in 1 only the aortic valve was replaced. A combined transeptal and superior approach was used for all patients. The CPV was performed after the valvular procedure with cryothermy at -60°C for 2 minutes with two 15 mm cryoprobes applied simultaneously. Results: CPV increased surgical time by 10 to 20 minutes. Operative mortality was 4.8 percent (1 patient). One patient developed a pericardial effusion and another a complete heart block that required a permanent pacemaker. All patients improved their functional class. At the end of an average 10.5 months of follow-up, 50 percent of patients were in normal sinus rhythm and 25 percent persisted in AF. The remaining patients were in some type of regular rhythm. Conclusions: CPV as a complementary procedure in patients with AF undergoing valvular surgery had good results to abate AF. It restored normal sinus rhythm in 50 percent of the cases, with low morbidity and mortality and little increment in surgical time.


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Atrial Fibrillation/surgery , Cardiac Surgical Procedures/methods , Catheter Ablation/methods , Cryosurgery/methods , Pulmonary Veins/surgery , Atrial Fibrillation/mortality , Cardiac Surgical Procedures/mortality , Catheter Ablation/mortality , Follow-Up Studies , Heart Atria/surgery , Heart Valve Prosthesis Implantation , Treatment Outcome
10.
Rev. méd. Chile ; 134(9): 1135-1145, sept. 2006. ilus, tab
Article in Spanish, English | LILACS | ID: lil-438416

ABSTRACT

Background: Cardiac tumors are very uncommon at all ages. There are important clinical differences between children and adults in the behavior of these tumors. Aim: To compare the behavior of primary and secondary cardiac tumors, from fetal age to adults. Patients and Method: Multicentric retrospective analysis of 38 children and adults with cardiac tumors, evaluated with echocardiography between January 1995 and August 2001. Medical records, echocardiographic and radiological examinations, surgical protocols and pathologic examinations were reviewed. Follow-up was obtained through data on medical records or calling patients by telephone. Results: Tumors were diagnosed in 38 patients (13 children and 25 adults), from a total of 31.800 echocardiograms. In children the diagnosis was made by fetal, transthoracic or transesophageal echocardiography in 23.6 percent and 8 percent of cases, respectively. Eighty five percent were primary (10 benign and 1 malignant) and 15 percent, secondary tumors. Fifty four percent were rhabdomyomas and 75 percent regressed spontaneously. Seventy seven percent were symptomatic and 31 percent were treated with surgery. During a follow up of 44±35 months, 31 percent of patients died. In adults, 76 percent of tumors were diagnosed by transthoracic and 20 percent by transesophageal echocardiography. Seventy six percent were primary (18 benign and 1 malignant) and 24 percent secondary tumors. Fifty six percent were myxomas. Ninety two percent were symptomatic and 84 percent were treated surgically. Twenty percent of patients died in the early postoperative period. No adult patients had a follow-up. Conclusions: Rhabdomyomas were solely found in children. In adults, myxomas are the predominat cardiac tumors. Primary and metastasic malignant tumors are observed both in children and in adults.


Subject(s)
Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Middle Aged , Pregnancy , Heart Neoplasms , Rhabdomyoma , Chile/epidemiology , Echocardiography , Fetal Heart , Fibroma/epidemiology , Fibroma , Follow-Up Studies , Heart Neoplasms/epidemiology , Myxoma/epidemiology , Myxoma , Retrospective Studies , Rhabdomyoma/epidemiology , Ultrasonography, Prenatal
11.
Rev. méd. Chile ; 134(8): 1019-1023, ago. 2006. ilus
Article in Spanish, English | LILACS | ID: lil-438373

ABSTRACT

Hospitalization and death due to heart failure and cardiogenic shock is frequent and currently is increasing among the adult population. Although cardiac transplantation is the most effective treatment in patients with end-stage heart failure, its availability is limited. While waiting for transplantation, some patients become refractory to treatment and deteriorate progressively. Secondary multi-organ damage could highly compromise the transplant success and also could contraindicate it. Mechanical ventricular assist devices allow reestablishing normal cardiac output and they have been used as a bridge to recovery and transplantation. We report four patients that underwent mechanical ventricular support using the ABIOMED BVS 5000® system as a bridge for transplantation. Two patients were connected to biventricular assistance; a third patient was connected to a left ventricular support and the fourth to a right ventricular support. Three were successfully transplanted and one died of refractory non-cardiogenic shock. There were no complications related to the support system, such as infection, hemorrhage or stroke. In our experience, the ABIOMED BVS 5000® was an effective strategy as a bridge to heart transplant in patients in cardiogenic shock.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Heart Failure/therapy , Heart Transplantation , Heart-Assist Devices , Shock, Cardiogenic/therapy , Chile , Equipment Design , Fatal Outcome
12.
Rev. méd. Chile ; 134(5): 575-580, mayo 2006. tab
Article in Spanish | LILACS | ID: lil-429863

ABSTRACT

Background: Surgery of the aortic arch is a very complex procedure since it requires protective strategies for the brain, heart and rest of the body. Aim: To communicate our experience in the first 23 total or partial replacements of aortic arch. Material and methods: Retrospective search in the database of the Cardiovascular Surgery Unit for patients subjected to partial or total replacement of the aortic arch since 1998. Results: Between 1988 and 2002, 23 patients were operated. Seventeen had aortic dissection (10 acute and 7 chronic), five had an atherosclerotic aneurysm and one had a traumatic lesion. Thirteen patients were subjected to a replacement of the arch plus ascending aorta, six to a replacement of the arch plus descending aorta and four to a replacement of the arch, ascending and descending aorta. Seven patients had previous operation of the thoracic aorta. Arterial perfusion was done via the femoral artery, axillary artery or a combination of both. A hypothermic circulatory arrest was induced in 22; it was associated with cerebral retro perfusion alone in 8 patients, antegrade cerebral perfusion in 5; isolated or associated axillary perfusion was used in five patients. In seven, procedures on the aortic or mitral valve, or coronary artery operations were added. Operative mortality was 26%, 3 of the 8 patients operated as an emergency and 3 of 15 elective operations. There was no mortality among those without dissection and of 7 chronic dissections, one died. All patients were followed for an average of 45 months. Two patients required reinterventions on the aorta and one for colon cancer. There was one late death of unknown cause. Postoperative complications were agitation, bleeding and temporary vocal cord dysfunction. Conclusions: There is a learning curve, where more extensive operations, particularly those done as emergency or for dissections, had an increased operative risk.


Subject(s)
Female , Humans , Male , Middle Aged , Aortic Dissection/surgery , Aorta, Thoracic/surgery , Aortic Aneurysm, Thoracic/surgery , Aortic Dissection/mortality , Aortic Aneurysm, Thoracic/mortality , Brain/blood supply , Circulatory Arrest, Deep Hypothermia Induced , Extracorporeal Circulation , Retrospective Studies , Treatment Outcome
13.
Rev. méd. Chile ; 134(5): 635-640, mayo 2006. ilus
Article in Spanish | LILACS | ID: lil-429871

ABSTRACT

Primary cardiac tumors are uncommon in pediatric patients. We report a two year-old boy, who presented a recurrent left atrial myxoma. He was referred for cardiologic evaluation because of cardiomegaly on a chest X-ray. An echocardiography showed a big left atrial tumor attached to the atrial septum. The tumor was uneventfully removed and the pathological examination confirmed a myxoma. He remained asymptomatic and during a follow up echocardiography two years later, a recurrent tumor was noted. He was successfully operated again, remaining free of a new recurrence after 3 years of follow up.


Subject(s)
Child, Preschool , Humans , Male , Heart Neoplasms/surgery , Myxoma/surgery , Neoplasm Recurrence, Local/surgery , Heart Atria/pathology , Heart Atria/surgery , Heart Atria , Heart Neoplasms/pathology , Heart Neoplasms , Myxoma/pathology , Myxoma , Neoplasm Recurrence, Local/pathology , Neoplasm, Residual/pathology , Neoplasm, Residual/surgery , Treatment Outcome
14.
Rev. méd. Chile ; 133(10): 1139-1146, oct. 2005. tab, graf
Article in Spanish | LILACS | ID: lil-420141

ABSTRACT

Background: Mitral valve repair is considered better than mitral valve replacement for degenerative mitral regurgitation. Aim: To evaluate late clinical results of mitral valve repair as compared to mitral valve replacement in patients with degenerative mitral regurgitation. Patients and methods: All patients subjected to open heart surgery for degenerative mitral regurgitation between 1990 and 2002 were assessed for surgical mortality, late cardiac and overall mortality, reoperation, readmission to hospital, functional capacity and anticoagulant therapy. Eighty eight patients (48 males) had mitral valve repair and 28 (19 males) had mitral valve replacement (23 with a mechanical prosthesis). Mean age was 59.9 ± 14.8 (SD) and 61.3 ± 14.6 years, respectively. Sixty three percent of patients with repair and 50% of those with valve replacement were in functional class III or IV before surgery. Results: Operative mortality was 2.3% for mitral valve repair and 3.6% for mitral valve replacement (NS). Also, there was no statistical difference in the need of reoperation during the follow-up period between both procedures (2.3% and 0%, respectively). Ninety four percent of the replacement patients but only 26% of the repair patients were in anticoagulant therapy at the end of the follow-up period (p <0.001). Ten years survival rates were 82 ± 6% for mitral valve repair and 54 ± 11% for replacement. The corresponding cardiac related survival rates were 89 ± 6% and 79 ± 10%. At the end of follow-up, all surviving patients were in functional class I or II. Ten years freedom from cardiac event rates (death, cardiac related rehospitalization and reoperation) were 90 ± 3% for mitral valve repair and 84 ± 6% for replacement. Conclusion: Repair of the mitral valve offers a better overall survival and a better chance of freedom from cardiac events as well as need for anticoagulation 10 years after surgery.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Heart Valve Prosthesis Implantation/standards , Mitral Valve Insufficiency/surgery , Mitral Valve/surgery , Chile/epidemiology , Disease-Free Survival , Follow-Up Studies , Heart Valve Prosthesis Implantation/mortality , Hospitalization , Mitral Valve Insufficiency/mortality , Mitral Valve Insufficiency/pathology , Mitral Valve/pathology , Reoperation , Survival Rate , Treatment Outcome
15.
Rev. méd. Chile ; 133(9): 1065-1070, sept. 2005. ilus, tab
Article in Spanish | LILACS | ID: lil-429244

ABSTRACT

Extracorporeal membrane oxygenation (ECMO) improves survival in neonatal and pediatric patients with reversible severe respiratory or cardiac failure, in whom intensive treatment fails. Since 1999, a multidisciplinary team is trained to form the first neonatal-pediatric ECMO center in Chile, according to the norms of the Extracorporeal Life Support Organization (ELSO). During 2003 the first three patients were admitted to the program: a male newborn with pulmonary hypertension, a 38 days old female operated for a total anomalous pulmonary venous connection and a 3 months old male with a severe pneumonia caused by respiratory syncytial virus. They remained in ECMO for five, seven and nine days respectively and all survived to the procedure. No neurological complications were observed after one and a half year of follow up. This consolidates the first national neonatal-pediatric ECMO program, associated to ELSO. Up to date, twelve patients have been admitted to the program.


Subject(s)
Female , Humans , Infant , Infant, Newborn , Male , Heart Failure , Extracorporeal Membrane Oxygenation/standards , Hypertension, Pulmonary/therapy , Intensive Care, Neonatal/standards , Respiratory Insufficiency/therapy , Chile , Intensive Care Units, Neonatal/standards , Program Evaluation
16.
Rev. chil. pediatr ; 76(4): 375-383, ago. 2005. ilus, tab, graf
Article in Spanish | LILACS | ID: lil-433004

ABSTRACT

Antecedentes: El reemplazo valvular mitral (RVM) y aórtico (RVA) es poco frecuente en pacientes pediátricos y las series publicadas reportan elevada morbi-mortalidad. Objetivo: Evaluar los resultados a mediano plazo en niños sometidos a RVM y RVA durante los últimos diez años, con el fin de determinar morbimortalidad y calidad de vida. Método: Análisis retrospectivo de 26 niños consecutivos (mediana de edad 5,6 años) sometidos a RVM y RVA, entre marzo 1992 y junio 2003. Diecisiete presentaban patología mitral y once aórtica. Resultados: Se realizaron 26 operaciones implantando 28 prótesis (26 mecánicas y 2 biológicas). Tres pacientes (12 por ciento) fallecieron durante el primer mes. La mediana de seguimiento fue de 6,2 años. Tres pacientes con RVM fallecieron alejadamente por causa no atribuible al reemplazo valvular con una sobrevida actuarial de 87 por ciento. Tres pacientes requirieron reoperación. Todos realizan actividades adecuadas a su edad, restringiéndose los deportes de contacto. Conclusión: Los resultados a mediano plazo del reemplazo valvular en niños con valvulopatía grave son satisfactorios.


Subject(s)
Male , Adolescent , Humans , Female , Infant , Child, Preschool , Child , Heart Valve Prosthesis , Heart Valve Prosthesis Implantation , Aortic Valve/surgery , Mitral Valve/surgery , Anticoagulants/therapeutic use , Bioprosthesis , Follow-Up Studies , Heart Valve Prosthesis Implantation/instrumentation , Heart Valve Prosthesis Implantation/mortality , Prosthesis Failure , Reoperation , Retrospective Studies , Survival Rate , Treatment Outcome
17.
Rev. méd. Chile ; 133(4): 403-408, abr. 2005. ilus
Article in Spanish | LILACS | ID: lil-417377

ABSTRACT

Background: Mortality of traumatic aortic lesions is over 80 percent. A group of those who survive, develop a chronic pseudo aneurism, usually asymptomatic, that is detected during imaging studies. Since conventional surgical treatment of traumatic aortic lesions has a great mortality, endovascular treatment has been used as an alternative treatment in the last decade. Aim: To report our experience with endovascular treatment of traumatic aortic lesions. Patients and methods: Report of seven patients aged 22 to 65 years, with traumatic aortic lesions. Under general anesthesia an endovascular prosthesis was inserted through the femoral artery. Results: No complications were observed in the postoperative period, and after a follow up ranging from 4 to 40 months, no endoleaks or other complications have been detected. Conclusions: Endovascular treatment of traumatic aortic lesions has good immediate and midterm results.


Subject(s)
Humans , Male , Adult , Female , Middle Aged , Aorta, Thoracic/surgery , Aortic Rupture/surgery , Aortic Rupture/etiology , Follow-Up Studies , Postoperative Period
18.
Rev. méd. Chile ; 133(3): 279-286, mar. 2005. ilus, tab
Article in Spanish | LILACS | ID: lil-404883

ABSTRACT

Background: Surgical valve repair is a good alternative for correction of incompetent bicuspid aortic valve. Aim: To report the early and late surgical, clinical and ecochardiographic results of surgical repair of incompetent bicuspid aortic valves. Patients and methods: Retrospective review of medical records of 18 patients aged 19 to 61 years, with incompetent bicuspid aortic valve in whom a valve repair was performed. Four patients had infectious endocarditis and 17 were in functional class I or II. Follow up ranged from 3 to 113 months after surgery. Results: A triangular resection of the prolapsing larger cusp, which included the middle raphe, was performed in 17 cases; in 13 of these, a complementary subcommisural annuloplasty was performed. In the remaining case, with a perforation of the non-coronary cusp, a pericardial patch was implanted; this procedure was also performed in 2 other cases. In 3 cases large vegetations were removed. Postoperative transesophageal echocardiography showed no regurgitation in 11 patients (62percent) and mild regurgitation in 7 (38percent). There was no operative morbidity or mortality. There were no deaths during the follow-up period. In 3 patients (17percent) the aortic valve was replaced with a mechanical prosthesis, 8 to 108 months after the first operation. Reoperation was not needed in 93percent±6,4percent at 1 year and 85percent±9,5percentat 5 years, these patients were all in functional class I at the end of the follow-up period. 60percen had no aortic regurgitation, 20percent had mild and 20percent moderate aortic regurgitation on echocardiographic examination. A significant reduction of the diastolic diameter of the left ventricle was observed, but there were no significant changes in systolic diameter or shortening fraction. Conclusions: Surgical repair of incompetent bicuspid aortic valves has low operative morbidity and mortality and has a low risk of reoperation.


Subject(s)
Adult , Male , Humans , Middle Aged , Aortic Valve Insufficiency/surgery , Aortic Valve Insufficiency/etiology , Aortic Valve/abnormalities , Aortic Valve/surgery , Echocardiography , Follow-Up Studies
19.
Rev. méd. Chile ; 132(5): 556-563, mayo 2004. ilus, tab
Article in Spanish | LILACS | ID: lil-384413

ABSTRACT

Background: Norwood procedure is used as the first stage in the palliative treatment of the hypoplastic heart syndrome and can be used, with some technical modifications, in other forms of univentricular heart with aortic stenosis or hypoplasia. These patients have a high mortality (50 percent), derived from the procedure itself and from their abnormal physiological status. Aim: To report our experience with the Norwood procedure. Patients and methods: Retrospective analysis of all patients subjected to the Norwood procedure between February 2000 and June 2003. Results: Thirteen patients (9 females, age range 5-60 days and median weight of 3.3 kg) were operated. Eight had hypoplastic heart syndrome and five had a single ventricle with aortic arch hypoplasia. The diagnosis was done in utero in eight patients. All technical variations, according to the disposition and anatomy of the great vessels, are described. Cardiac arrest with profound hypothermia was used in all and regional cerebral perfusion was used in nine. Three patients died in the perioperative period and three died in the follow up (two, four and 10 months after the procedure). Gleen and Fontan procedures were completed in five and one patients, respectively. Conclusions: Our results with the Norwood procedure are similar to other series. There is an important mortality in the immediate operative period and prior to the Glenn procedure (Rev MÚd Chile 2004; 132: 556-63).


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Hypoplastic Left Heart Syndrome , Heart Defects, Congenital/surgery , Chile , Patient Selection
20.
Rev. méd. Chile ; 132(3): 307-315, mar. 2004. graf
Article in Spanish | LILACS | ID: lil-384172

ABSTRACT

Background: Valve replacement has been the treatment of choice for patients with valvular complications of infectious endocarditis (IE). However, excellent results with valve repair allowed it to become a new therapeutic alternative for these patients. Aim: To evaluate the results of valve repair in patients with valvular complications of IE. Patients and Methods: From January 1991 to December 2000, 14 patients with valvular complications of IE underwent valve repair. Mean age was 37.9 ± 14.9. Results: New York Heart Association (NYHA) class was 2.8 ± 0.9. IE was located in the aortic in 6 (42 percent), in the mitral valve in 4 (29 percent) and in both valves in 4 cases (29 percent). Surgical indication was hemodynamic in 50 percent of the cases, echocardiographic in 29 percent and septic in 21 percent. Five aortic valves were bicuspid, 3 mitral valves were myxomatous and the rest were normal. The most common septic lesions were vegetations and leaflet perforations. A total of 23 aortic and 21 mitral valve repair procedures were performed. There were no deaths. Only 1 patient had a surgical complication (renal failure and prolonged mechanical ventilation). Follow-up was 100 percent complete. There was not late mortality. One patient with bone marrow aplasia required reoperation for a new episode of IE 19 months later. At the end of the follow-up NYHA class was 1.3 ± 0.6 and echocardiography showed a mild or absence of valve regurgitation in most patients. Conclusions: Valve repair surgery in IE has good results, with advantages over valve replacement (Rev MÚd Chile 2004; 132: 307-15).


Subject(s)
Humans , Male , Female , Endocarditis, Bacterial , Endocarditis, Bacterial/surgery , Heart Valves/surgery
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